• New information on HCV prevalence, treatment, and management of reinfection among persons who inject drugs

• Updated to reflect that no dose adjustments are required for any recommended DAA regimen for patients with severe renal impairment

• Updated mother-to-child HCV transmission rates

• New data on the safety and efficacy of DAAs in pregnancy

Addition of information from the National Comprehensive Cancer Network’s guideline on Cancer in People With HIV

• Information on incidence of NADCs in people with HIV compared with people who do not have HIV from NA-ACCORD

• New information from HIVMA/IDSA Primary Care Guidelines related to screening strategies for NADCs

• Revised anal cancer classification from the World Health Organization